磷酸尿苷葡萄糖

磷酸尿苷葡萄糖用途

Uridine 5′-diphosphoglucose disodium salt (UDP-D-Glucose disodium salt) 是动物组织和某些微生物中含有葡萄糖的寡糖、多糖、糖蛋白和糖脂的前体。Uridine 5′-diphosphoglucose disodium salt (UDP-D-Glucose disodium salt) 是一种 P2Y14 受体 (一种神经免疫系统 GPCR) 激动剂。

磷酸尿苷葡萄糖名称

[ CAS 号 ]:
28053-08-9

[ 中文名 ]:
二磷酸尿苷葡萄糖二钠盐

[ 英文名 ]:
Uridine 5′-diphosphoglucose disodium salt

[中文别名 ]:

[英文别名 ]:

UDP-Glc UDP-glucose UDPG
UDP-glc

磷酸尿苷葡萄糖生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 神经疾病

[参考文献]

[1]. DietrichKeppler, et al. Uridine-5′-diphosphoglucose. Methods of Enzymatic Analysis (Second English Edition). 1974;4:2225-2228.

[2]. Das A, et al. Human P2Y(14) receptor agonists: truncation of the hexose moiety of uridine-5'-diphosphoglucose and its replacement with alkyl and aryl groups. J Med Chem. 2010 Jan 14;53(1):471-80.

磷酸尿苷葡萄糖物理化学性质

[ 密度 ]:
1.9±0.1 g/cm3

[ 沸点 ]:
780.3±70.0 °C at 760 mmHg

[ 分子式 ]:
C₁₅H₂₂N₂Na₂O₁₇P₂

[ 分子量 ]:
456.231

[ 闪点 ]:
425.7±35.7 °C

[ 精确质量 ]:
456.043396

[ PSA ]:
330.11000

[ LogP ]:
-4.05

[ 外观性状 ]:
白色至灰白色固体

[ 蒸汽压 ]:
0.0±6.1 mmHg at 25°C

[ 折射率 ]:
1.612

[ 储存条件 ]:
−20°C

[ 水溶解性 ]:
H2O: soluble50mg/mL, clear

磷酸尿苷葡萄糖MSDS

详细MSDS(安全技术说明书)

磷酸尿苷葡萄糖安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
29400090

磷酸尿苷葡萄糖文献

Hysteresis in human UDP-glucose dehydrogenase is due to a restrained hexameric structure that favors feedback inhibition.

Biochemistry 53(51) , 8043-51, (2014)

Human UDP-α-d-glucose-6-dehydrogenase (hUGDH) displays hysteresis because of a slow isomerization from an inactive state (E*) to an active state (E). Here we show that the structure of E* constrains h...

Transporter-mediated uptake of UDP-glucuronic acid by human liver microsomes: assay conditions, kinetics, and inhibition.

Drug Metab. Dispos. 43(1) , 147-53, (2014)

This study characterized the kinetics, variability, and factors that affect UDP-glucuronic acid (UDP-GlcUA) uptake by human liver microsomes (HLM). Biphasic kinetics were observed for UDP-GlcUA uptake...

UDP-glucose pyrophosphorylase influences polysaccharide synthesis, cell wall components, and hyphal branching in Ganoderma lucidum via regulation of the balance between glucose-1-phosphate and UDP-glucose.

Fungal Genet. Biol. 82 , 251-63, (2015)

UDP-glucose pyrophosphorylase (UGP) is a key enzyme involved in carbohydrate metabolism, but there are few studies on the functions of this enzyme in fungi. The ugp gene of Ganoderma lucidum was clone...

更多文献

磷酸尿苷葡萄糖

磷酸尿苷葡萄糖用途

磷酸尿苷葡萄糖名称

磷酸尿苷葡萄糖生物活性

磷酸尿苷葡萄糖物理化学性质

磷酸尿苷葡萄糖MSDS

详细MSDS(安全技术说明书)

磷酸尿苷葡萄糖安全信息

磷酸尿苷葡萄糖文献

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