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呋喃酮C-30

呋喃酮C-30用途

呋喃酮C-30是一种合成呋喃酮细菌群体感应抑制剂。呋喃酮C-30抑制铜绿假单胞菌毒力因子表达,增加细菌对抗生素的敏感性。

呋喃酮C-30名称

[ CAS 号 ]:
247167-54-0

[ 中文名 ]:
呋喃酮C-30

[ 英文名 ]:
Furanone C-30

[中文别名 ]:

[英文别名 ]:

Furanone C-30
(5Z)-4-Bromo-5-(bromomethylene)-2(5H)-furanone
(5Z)-4-Bromo-5-(bromomethylene)-2(5H)-furanone

呋喃酮C-30生物活性

[ 描述 ]:

呋喃酮C-30是一种合成呋喃酮细菌群体感应抑制剂。呋喃酮C-30抑制铜绿假单胞菌毒力因子表达,增加细菌对抗生素的敏感性。

[ 相关类别 ]:

信号通路 >> 抗感染 >> 细菌

呋喃酮C-30物理化学性质

[ 密度 ]:
2.650±0.06 g/cm3

[ 沸点 ]:
205.9±40.0 ºC (760 Torr)

[ 熔点 ]:
97-99 ºC

[ 分子式 ]:
C₅H₂Br₂O₂

[ 分子量 ]:
253.87600

[ 闪点 ]:
78.3±27.3 ºC

[ 精确质量 ]:
251.84200

[ PSA ]:
26.30000

[ LogP ]:
2.05830

[ 外观性状 ]:
结晶

[ 储存条件 ]:
20°C

[ 水溶解性 ]:
Slightly soluble (6.3 g/L) (25 ºC)

呋喃酮C-30MSDS

详细MSDS(安全技术说明书)

呋喃酮C-30安全信息

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2932209090

呋喃酮C-30海关

[ 海关编码 ]: 2932209090

[ 中文概述 ]:
2932209090. 其他内酯. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

呋喃酮C-30文献

Synthetic furanones inhibit quorum-sensing and enhance bacterial clearance in Pseudomonas aeruginosa lung infection in mice.

J. Antimicrob. Chemother. 53(6) , 1054-1061, (2004)

Antibiotics are used to treat bacterial infections by killing the bacteria or inhibiting their growth, but resistance to antibiotics can develop readily. The discovery that bacterial quorum-sensing re...

The use of (5Z)-4-bromo-5-(bromomethylene)-2(5H)-furanone for controlling acid mine drainage through the inhibition of Acidithiobacillus ferrooxidans biofilm formation.

Bioresour. Technol. 186 , 52-7, (2015)

The aim of this study was to determine whether acid mine drainage (AMD) production can be decreased by (5Z)-4-bromo-5-(bromomethylene)-2(5H)-furanone (furanone C-30) in the presence of Acidithiobacill...

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