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还原型 S-己基-L-谷胱甘肽

还原型 S-己基-L-谷胱甘肽用途

S-己基谷胱甘肽是一种S-取代的谷胱甘肽,其中硫醇的氢被己基取代。S-己基谷胱甘肽也是谷胱甘肽-S-转移酶的竞争性抑制剂。S-己基谷胱甘肽可以用作谷胱甘肽-S-转移酶和谷胱甘肽过氧化物酶的亲和色谱配体[1][2]。

还原型 S-己基-L-谷胱甘肽名称

[ CAS 号 ]:
24425-56-7

[ 中文名 ]:
还原型 S-己基-L-谷胱甘肽

[ 英文名 ]:
NSC 131114

[英文别名 ]:

S-Hexylglutathione
MFCD00056735

还原型 S-己基-L-谷胱甘肽生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[体外研究]

S-己基谷胱甘肽与人谷胱甘肽转移酶P1-1结合,Kd值分别为3.7μM(Y49F突变体)和1.27μM(野生型)[1]。

还原型 S-己基-L-谷胱甘肽物理化学性质

[ 密度 ]:
1.254g/cm3

[ 沸点 ]:
748.5ºC at 760 mmHg

[ 熔点 ]:
200-202ºC(lit.)

[ 分子式 ]:
C₁₆H₂₉N₃O₆S

[ 分子量 ]:
391.48300

[ 闪点 ]:
406.5ºC

[ 精确质量 ]:
391.17800

[ PSA ]:
184.12000

[ LogP ]:
1.65970

[ 蒸汽压 ]:
1.61E-24mmHg at 25°C

[ 折射率 ]:
1.54

还原型 S-己基-L-谷胱甘肽MSDS

还原型 S-己基-L-谷胱甘肽安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2930909090

还原型 S-己基-L-谷胱甘肽合成路线

还原型 S-己基-L-谷胱甘肽上下游产品

还原型 S-己基-L-谷胱甘肽上游产品

还原型 S-己基-L-谷胱甘肽下游产品

还原型 S-己基-L-谷胱甘肽海关

[ 海关编码 ]: 2930909090

[ 中文概述 ]:
2930909090. 其他有机硫化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

还原型 S-己基-L-谷胱甘肽文献

Quantitation of protein S-glutathionylation by liquid chromatography-tandem mass spectrometry: correction for contaminating glutathione and glutathione disulfide.

Anal. Biochem. 469 , 54-64, (2014)

Protein S-glutathionylation is a posttranslational modification that links oxidative stimuli to reversible changes in cellular function. Protein-glutathione mixed disulfide (PSSG) is commonly quantifi...

Effects of ONO-6950, a novel dual cysteinyl leukotriene 1 and 2 receptors antagonist, in a guinea pig model of asthma.

Eur. J. Pharmacol. 765 , 242-8, (2015)

We assessed in this study the anti-asthmatic effects of ONO-6950, a novel cysteinyl leukotriene 1 (CysLT1) and 2 (CysLT2) receptors dual antagonist, in normal and S-hexyl glutathione (S-hexyl GSH)-tre...

Glutathionylation and Reduction of Methacrolein in Tomato Plants Account for Its Absorption from the Vapor Phase.

Plant Physiol. 169 , 1744-54, (2015)

A large portion of the volatile organic compounds emitted by plants are oxygenated to yield reactive carbonyl species, which have a big impact on atmospheric chemistry. Deposition to vegetation driven...

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