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3-苯基-2-硫代乙内酰脲

3-苯基-2-硫代乙内酰脲用途

电池材料

3-苯基-2-硫代乙内酰脲名称

[ CAS 号 ]:
2010-15-3

[ 中文名 ]:
苯基乙内酰脲-甘氨酸

[ 英文名 ]:
PTH-glycine

[中文别名 ]:

[英文别名 ]:

3-phenyl-2-thio-hydantoi
3-(phenyl)-2-thioxo-4-imidazolidinone
3-PHENYL-2-THIOXO-4-IMIDAZOLIDINONE
3-Phenyl-2-thiohydantoin
3-phenyl-2-thioguidanthion
glycine,3-phenyl-2-thiohydantoin
EINECS 217-927-3
PHENYLTHIOHYDANTOIN-DL-GLYCINE
(E)-2-cyano-3-(4-fluorophenyl)prop-2-enethioamide
PHENYLTHIOHYDANTOIN-GLYCINE

3-苯基-2-硫代乙内酰脲物理化学性质

[ 密度 ]:
1.39g/cm3

[ 沸点 ]:
292.1ºC at 760mmHg

[ 分子式 ]:
C₉H₈N₂OS

[ 分子量 ]:
192.23800

[ 闪点 ]:
130.5ºC

[ 精确质量 ]:
192.03600

[ PSA ]:
64.43000

[ LogP ]:
1.30150

[ 外观性状 ]:
固体;Light yellow to Brown powder to crystal

[ 折射率 ]:
1.684

[ 储存条件 ]:
−20°C

3-苯基-2-硫代乙内酰脲MSDS

3-苯基-2-硫代乙内酰脲毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MU4025000

CHEMICAL NAME :: Hydantoin, 3-phenyl-2-thio-

CAS REGISTRY NUMBER :: 2010-15-3

BEILSTEIN REFERENCE NO. :: 0152535

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H8-N2-O-S

MOLECULAR WEIGHT :: 192.25

WISWESSER LINE NOTATION :: T5MYNV EHJ BUS CR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 155 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRZKAP Farmatsevtichnii Zhurnal (Kiev). (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.3- 1930- Volume(issue)/page/year: 17(1),36,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 75 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490

3-苯基-2-硫代乙内酰脲安全信息

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301-H311-H331

[ 警示性声明 ]:
P261-P280-P301 + P310-P311

[ 个人防护装备 ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T: Toxic;

[ 风险声明 (欧洲) ]:
23/24/25

[ 安全声明 (欧洲) ]:
S36/37/39-S45

[ 危险品运输编码 ]:
UN 2811 6.1/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
MU4025000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)

[ 海关编码 ]:
2933990090

3-苯基-2-硫代乙内酰脲合成路线

3-苯基-2-硫代乙内酰脲上下游产品

3-苯基-2-硫代乙内酰脲上游产品

3-苯基-2-硫代乙内酰脲下游产品

3-苯基-2-硫代乙内酰脲海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

3-苯基-2-硫代乙内酰脲文献

Differential androgen deprivation therapies with anti-androgens casodex/bicalutamide or MDV3100/Enzalutamide versus anti-androgen receptor ASC-J9(R) Lead to promotion versus suppression of prostate cancer metastasis.

J. Biol. Chem. 288(27) , 19359-69, (2013)

Despite the fact that androgen deprivation therapy (ADT) can effectively reduce prostate cancer (PCa) size, its effect on PCa metastasis remains unclear. We examined the existing data on PCa patients ...

Interactions of abiraterone, eplerenone, and prednisolone with wild-type and mutant androgen receptor: a rationale for increasing abiraterone exposure or combining with MDV3100.

Cancer Res. 73(9) , 2926, (2013)

Combined blockade of testicular and locally made androgens in prostate cancer: a highly significant medical progress based upon intracrinology.

J. Steroid Biochem. Mol. Biol. 145 , 144-56, (2015)

Recently two drugs, namely the antiandrogen MDV-3100 and the inhibitor of 17α-hydroxylase abiraterone have been accepted by the FDA for the treatment of castration-resistant prostate cancer (CRPC) wit...

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