D-氨基半乳糖盐酸盐

D-氨基半乳糖盐酸盐用途

D(+)-半乳糖胺(D-半乳糖胺)盐酸盐是一种已确定的实验毒素,主要通过产生自由基和消耗UTP核苷酸引起肝损伤。D(+)-半乳糖胺盐酸盐中毒也会导致肾功能不全,因此,肾功能衰竭通常和终末期肝损伤有关。脂多糖/D(+)-半乳糖胺诱导的急性肝损伤是一种已知的暴发性肝衰竭动物模型[1][2]。

D-氨基半乳糖盐酸盐名称

[ CAS 号 ]:
1772-03-8

[ 中文名 ]:
2-氨基-2-脱氧-D-半乳糖盐酸盐

[ 英文名 ]:
D-(+)-Galactosamine hydrochloride

[中文别名 ]:

[英文别名 ]:

Galactosamine
D-GalactosaMine HC1
2-deoxy-2-amino-D-galactose hydrochloride
GALACTOSAMINE HCL
2-aMino-2-deoxy-L-idose
D-GALN HCL
D-(+)-Galactosamine hydrochloride
2-amino-2-deoxy-D-galactopyranose hydrochloride
Chondrosamine Hydrochloride
D-GALACTOSAMINE HCL

D-氨基半乳糖盐酸盐生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 炎症/免疫

[参考文献]

[1]. Ayhanci A, et al. Protective effects of ellagic acid in D-galactosamine-induced kidney damage in rats. Cytotechnology. 2016;68(5):1763-1770.

[2]. Okumura A, et al. Alleviation of lipopolysaccharide/d-galactosamine-induced liver injury in leukocyte cell-derived chemotaxin 2 deficient mice. Biochem Biophys Rep. 2017;12:166-171. Published 2017 Oct 13.

D-氨基半乳糖盐酸盐物理化学性质

[ 沸点 ]:
532.5ºC at 760 mmHg

[ 熔点 ]:
182-185 °C (dec.)(lit.)

[ 分子式 ]:
C₆H₁₄ClNO₅

[ 分子量 ]:
215.63

[ 闪点 ]:
275.8ºC

[ 精确质量 ]:
215.056046

[ PSA ]:
116.17000

[ 外观性状 ]:
白色粉末

[ 蒸汽压 ]:
5.53E-10mmHg at 25°C

[ 折射率 ]:
96 ° (C=1, H2O)

[ 储存条件 ]:
2~8°C

[ 水溶解性 ]:
SOLUBLE

D-氨基半乳糖盐酸盐MSDS

D-氨基半乳糖盐酸盐安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
LW5500000

[ 海关编码 ]:
2922399090

D-氨基半乳糖盐酸盐合成路线

D-氨基半乳糖盐酸盐上下游产品

D-氨基半乳糖盐酸盐上游产品

D-氨基半乳糖盐酸盐下游产品

D-氨基半乳糖盐酸盐海关

[ 海关编码 ]: 2922399090

[ 中文概述 ]:
2922399090 其他氨基醛、氨基酮及其盐（包括氨基醌及其盐，但含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

D-氨基半乳糖盐酸盐文献

An ENU-induced splicing mutation reveals a role for Unc93b1 in early immune cell activation following influenza A H1N1 infection.

Genes Immun. 15(5) , 320-32, (2014)

Genetic and immunological analysis of host-pathogen interactions can reveal fundamental mechanisms of susceptibility and resistance to infection. Modeling human infectious diseases among inbred mouse ...

Towards a full integration of optimization and validation phases: An analytical-quality-by-design approach

J. Chromatogr. A. 1395 , 88-98, (2015)

• An enhanced quality-by-design strategy throughout the analytical method lifecycle. • Quantitative design space: an innovative approach for development of analytical methods. • Integrated approaches ...

Inhibition of plasmin attenuates murine acute graft-versus-host disease mortality by suppressing the matrix metalloproteinase-9-dependent inflammatory cytokine storm and effector cell trafficking.

Leukemia 29(1) , 145-56, (2015)

The systemic inflammatory response observed during acute graft-versus-host disease (aGVHD) is driven by proinflammatory cytokines, a 'cytokine storm'. The function of plasmin in regulating the inflamm...

更多文献

D-氨基半乳糖盐酸盐

D-氨基半乳糖盐酸盐用途

D-氨基半乳糖盐酸盐名称

D-氨基半乳糖盐酸盐生物活性

D-氨基半乳糖盐酸盐物理化学性质

D-氨基半乳糖盐酸盐MSDS

详细MSDS(安全技术说明书)

D-氨基半乳糖盐酸盐安全信息

D-氨基半乳糖盐酸盐合成路线

详细合成路线

D-氨基半乳糖盐酸盐上下游产品

D-氨基半乳糖盐酸盐上游产品

D-氨基半乳糖盐酸盐下游产品

D-氨基半乳糖盐酸盐海关

D-氨基半乳糖盐酸盐文献

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