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乙去氧尿啶

乙去氧尿啶用途

Edoxudine是一种抗病毒药物, 是胸苷类似物,对单纯疱疹病毒有效。

乙去氧尿啶名称

[ CAS 号 ]:
15176-29-1

[ 中文名 ]:
乙去氧尿啶

[ 英文名 ]:
Edoxudine

[中文别名 ]:

[英文别名 ]:

5-Ethyl-2'-deoxyuridine
2'-deoxy-5-ethyluridine
EUdR Edoxudine
edu
edoxudin
Etudr
5-Ethyl-durd
aedurid
5-ethyldeoxyuridine
EDOXUDINE

乙去氧尿啶生物活性

[ 描述 ]:

Edoxudine是一种抗病毒药物, 是胸苷类似物,对单纯疱疹病毒有效。

[ 相关类别 ]:

信号通路 >> 抗感染 >> 细菌

研究领域 >> 感染

[相关活性小分子]

乙去氧尿啶物理化学性质

[ 密度 ]:
1.389 g/cm3

[ 熔点 ]:
152-153°

[ 分子式 ]:
C₁₁H₁₆N₂O₅

[ 分子量 ]:
256.25500

[ 精确质量 ]:
256.10600

[ PSA ]:
104.55000

[ 折射率 ]:
1.569

[ 储存条件 ]:
?20°C

乙去氧尿啶MSDS

乙去氧尿啶毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YU7500000

CHEMICAL NAME :: Uridine, 2'-deoxy-5-ethyl-

CAS REGISTRY NUMBER :: 15176-29-1

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C11-H16-N2-O5

MOLECULAR WEIGHT :: 256.29

WISWESSER LINE NOTATION :: T6NVMVJ F2 A- BT5OTJ E1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Rodent - rabbit Kidney

DOSE/DURATION :: 200 mg/L

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 24,1073,1975

乙去氧尿啶安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
YU7500000

[ 海关编码 ]:
29349990

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乙去氧尿啶文献

Sensitivity of monkey B virus (Cercopithecine herpesvirus 1) to antiviral drugs: role of thymidine kinase in antiviral activities of substrate analogs and acyclonucleosides.

Antimicrob. Agents Chemother. 51 , 2028-34, (2007)

Herpes B virus (B virus [BV]) is a macaque herpesvirus that is occasionally transmitted to humans where it can cause rapidly ascending encephalitis that is often fatal. To understand the low susceptib...

Pleiotrophin suppression of receptor protein tyrosine phosphatase-β/ζ maintains the self-renewal competence of fetal human oligodendrocyte progenitor cells.

J. Neurosci. 32(43) , 15066-75, (2012)

Oligodendrocyte progenitor cells (OPCs) persist in human white matter, yet the mechanisms by which they are maintained in an undifferentiated state are unknown. Human OPCs differentially express prote...

An in vitro study of ophthalmic antiviral agent toxicity on rabbit corneal epithelium.

Antiviral Res. 9(4) , 263-72, (1988)

Using an in vitro system we measured the corneal epithelial cytotoxicity and the antiviral activity of the antiviral agents idoxuridine (IDU), trifluridine (TFT), ethyldeoxyuridine (EDU), and (E)-5-(2...

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