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2,4,5-三甲基苯胺

2,4,5-三甲基苯胺名称

[ CAS 号 ]:
137-17-7

[ 中文名 ]:
2,4,5-三甲基苯胺

[ 英文名 ]:
pseudocumidine

[中文别名 ]:

2,4,5-三甲苯胺

[英文别名 ]:

2,4,5-trimethyl-aniline
5-amino-1,2,4-trimethyl-benzene
2,4,5-Trimethylphenylamin (Pseudocumidin)
2,4,5-trimethylphenylamine
Pseudokumidin [Czech]
pseudocumidine
2,4,5-TRIMETHYLANILINE
2,4,5-Trimethylbenzenamine
2,3-DIHYDRO-4-TRIFLUOROACETYL-1H-XANTENE
Aniline,2,4,5-trimethyl

2,4,5-三甲基苯胺物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
234.5±0.0 °C at 760 mmHg

[ 熔点 ]:
62 °C

[ 分子式 ]:
C₉H₁₃N

[ 分子量 ]:
135.206

[ 闪点 ]:
102.9±14.0 °C

[ 精确质量 ]:
135.104797

[ PSA ]:
26.02000

[ LogP ]:
2.32

[ 外观性状 ]:
无色至微红的黄色液体

[ 蒸汽压 ]:
0.1±0.4 mmHg at 25°C

[ 折射率 ]:
1.553

[ 储存条件 ]:
2-8°C

[ 稳定性 ]:
Stable. Combustible. Incompatible with strong oxidizing agents.

2,4,5-三甲基苯胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BZ0520000

CHEMICAL NAME :: Aniline, 2,4,5-trimethyl-

CAS REGISTRY NUMBER :: 137-17-7

LAST UPDATED :: 199510

DATA ITEMS CITED :: 19

MOLECULAR FORMULA :: C9-H13-N

MOLECULAR WEIGHT :: 135.23

WISWESSER LINE NOTATION :: ZR B1 D1 E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7000 mg/kg/101W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 17 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 28 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 68 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 35350 mg/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 70700 mg/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 141 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 566 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors

TYPE OF TEST :: Specific locus test

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - rat Fibroblast

DOSE/DURATION :: 148 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 211,279,1988 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 27,177,1982 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 27,177,1982 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-FINLAND;Carcinogen JAN 1993 OEL-GERMANY;Carcinogen JAN 1993 OEL-SWITZERLAND;Carcinogen JAN 1993

2,4,5-三甲基苯胺安全信息

[ 符号 ]:

GHS02, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H302 + H312 + H332-H319

[ 警示性声明 ]:
P210-P280-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
F: Flammable;Xn: Harmful;

[ 风险声明 (欧洲) ]:
R11;R20/21/22;R36

[ 安全声明 (欧洲) ]:
S16-S36/37-S61-S45-S53

[ 危险品运输编码 ]:
UN1648 3/PG 2

[ RTECS号 ]:
BZ0520000

[ 海关编码 ]:
2921499090

2,4,5-三甲基苯胺合成路线

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2,4,5-三甲基苯胺海关

[ 海关编码 ]: 2921430090

[ 中文概述 ]:
2921430090 甲苯胺及其衍生物以及它们的盐. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 原产地证据文件及编号(例附原产地证书, 原产于欧盟的

[ Summary ]:
HS:2921430090 toluidines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

2,4,5-三甲基苯胺文献

2,4,5- and 2,4,6-Trimethylaniline and their hydrochlorides.

IARC Monogr. Eval. Carcinog. Risk Chem. Hum. 27 , 177-88, (1982)

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