N-(1,1-二甲基乙基)-4-(2-甲氧基苯基)-ALPHA-苯基-1-哌嗪丙酰胺
用途
Way 100135 is a serotonergic drug of the phenylpiperazine family which is used in scientific research. It acts as potent 5-HT1A receptor antagonist, and was originally believed to be highly selective, but further studies have demonstrated that it also acts as a partial agonist of the 5-HT1D receptor (pKi = 7.58; virtually the same affinity for 5-HT1A), and to a much lesser extent, of the 5-HT1B receptor (pKi = 5.82). These findings may have prompted the development of the related compound WAY-100,635, another purportedly selective and even more potent 5-HT1A antagonist, which was synthesized shortly thereafter.
名称
[ CAS 号 ]:
133025-23-7
[ 中文名 ]:
(S)-n-叔丁基-3-(4-(2-甲氧基苯基)-哌嗪-1-基)-2-苯丙酰胺双盐酸盐
[ 英文名 ]:
Way100135
[中文别名 ]:
物理化学性质
[ 密度 ]:
1.085g/cm3
[ 沸点 ]:
582.8ºC at 760mmHg
[ 分子式 ]:
C24H35Cl2N3O2
[ 分子量 ]:
468.46000
[ 闪点 ]:
306.3ºC
[ 精确质量 ]:
467.21100
[ PSA ]:
44.81000
[ LogP ]:
5.51350
[ 蒸汽压 ]:
1.43E-13mmHg at 25°C
[ 折射率 ]:
1.556
推荐生产厂家/供应商:
热门化合物
CAS号[133025-23-7]化源网提供[N-(1,1-二甲基乙基)-4-(2-甲氧基苯基)-ALPHA-苯基-1-哌嗪丙酰胺]MSDS、说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。>>电脑版:N-(1,1-二甲基乙基)-4-(2-甲氧基苯基)-ALPHA-苯基-1-哌嗪丙酰胺
标题:133025-23-7_CAS号:133025-23-7_N-(1,1-二甲基乙基)-4-(2-甲氧基苯基)-ALPHA-苯基-1-哌嗪丙酰胺 - 化源网 地址:https://www.chemsrc.com/amp/cas/133025-23-7_1104951.html