133025-23-7

133025-23-7结构式

常用中文名：N-(1,1-二甲基乙基)-4-(2-甲氧基苯基)-ALPHA-苯基-1-哌嗪丙酰胺
常用英文名：Way100135
CAS号：133025-23-7
分子式：C₂₄H₃₅Cl₂N₃O₂
分子量：468.46000
发布时间：2018-10-19 16:25:12
更新时间：2024-04-03 20:17:05
Way 100135 is a serotonergic drug of the phenylpiperazine family which is used in scientific research. It acts as potent 5-HT1A receptor antagonist, and was originally believed to be highly selective, but further studies have demonstrated that it also acts as a partial agonist of the 5-HT1D receptor (pKi = 7.58; virtually the same affinity for 5-HT1A), and to a much lesser extent, of the 5-HT1B receptor (pKi = 5.82). These findings may have prompted the development of the related compound WAY-100,635, another purportedly selective and even more potent 5-HT1A antagonist, which was synthesized shortly thereafter.

中文名	(S)-n-叔丁基-3-(4-(2-甲氧基苯基)-哌嗪-1-基)-2-苯丙酰胺双盐酸盐
英文名	N-tert-butyl-3-[4-(2-methoxyphenyl)piperazin-1-yl]-2-phenylpropanamide
中文别名	N-(1,1-二甲基乙基)-4-(2-甲氧基苯基)-ALPHA-苯基-1-哌嗪丙酰胺