邻碘马尿酸钠
邻碘马尿酸钠用途
o-Iodohippurate sodium is an analogue of p-aminohippuric acid for the determination of effective renal plasma flow. Labelled OIH has a significantly higher clearance than other radiopharmaceutical yet developed and is eminently suitable for renography. It is eliminated mainly by tubular secretion. In patients with normally functioning kidneys, 85% of the OIH may be found in the urine 30 minutes after intravenous injection.
邻碘马尿酸钠名称
[ CAS 号 ]:
133-17-5
[ 中文名 ]:
邻碘马尿酸钠
[ 英文名 ]:
o-Iodohippurate sodium
[英文别名 ]:
- hippuran
- jodairol
- iodohippura
- medopaque
- Sodium iodohippurate
- EINECS 205-097-5
- iodairal
- renumbral
- orthoiodin
- iodohippuratesodium
邻碘马尿酸钠物理化学性质
[ 沸点 ]:
480.9ºC at 760mmHg
[ 分子式 ]:
C9H7INNaO3
[ 分子量 ]:
327.05100
[ 闪点 ]:
244.6ºC
[ 精确质量 ]:
326.93700
[ PSA ]:
69.23000
[ LogP ]:
0.16180
[ 蒸汽压 ]:
4.67E-10mmHg at 25°C
邻碘马尿酸钠毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MR8162000
- CHEMICAL NAME :
- Hippuric acid, o-iodo-, monosodium salt
- CAS REGISTRY NUMBER :
- 133-17-5
- LAST UPDATED :
- 199309
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C9-H7-I-N-O3.Na
- MOLECULAR WEIGHT :
- 327.06
- WISWESSER LINE NOTATION :
- OVIMVR BI &-NA-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 116,394,1956
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 42,721,1953
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- MECHAN Medicinal Chemistry, A Series of Reviews. (New York, NY) V.1-6, 1951-63. Discontinued. Volume(issue)/page/year: 6,290,1963
推荐生产厂家/供应商：
暂无推荐供应商。请联系客服获知如何成为推荐供应商。
相关化合物
【邻碘马尿酸钠】化源网提供邻碘马尿酸钠CAS号133-17-5，邻碘马尿酸钠MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询邻碘马尿酸钠上化源网，专业又轻松。>>电脑版：邻碘马尿酸钠
标题：邻碘马尿酸钠_用途_沸点_分子量_邻碘马尿酸钠CAS号【133-17-5】_化源网 地址：https://www.chemsrc.com/amp/cas/133-17-5_1183761.html