<生产厂家价格>

正壬醛

正壬醛用途

壬醛是一种具有止泻活性的饱和脂肪醛[1]。

正壬醛名称

[ CAS 号 ]:
124-19-6

[ 中文名 ]:
壬醛

[ 英文名 ]:
Nonanal

[中文别名 ]:

[英文别名 ]:

FEMA 2782
n-Nonaldehyde
NONENAL
EINECS 204-688-5
c-9aldehyde
Nononal
VH8
Pelargonaldehyde
Nonaldehyde
1-Nonanone

正壬醛生物活性

[ 描述 ]:

壬醛是一种具有止泻活性的饱和脂肪醛[1]。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 炎症/免疫

研究领域 >> 代谢疾病

[体外研究]

壬醛对蜡样双歧杆菌和单核细胞增生李斯特菌具有显著活性,MIC值均为7.8μg/ml[1]。

[体内研究]

壬醛对蓖麻油诱发的小鼠腹泻具有显著的抑制作用[1]。

[参考文献]

[1]. Miguel A, et al. Antidiarrhoeal Activity of Nonanal, an Aldehyde Isolated from Artemisia ludoviciana. Pharmaceutical Biology Volume 40, 2002 - Issue 4

正壬醛物理化学性质

[ 密度 ]:
0.8±0.1 g/cm3

[ 沸点 ]:
190.8±3.0 °C at 760 mmHg

[ 熔点 ]:
-18ºC

[ 分子式 ]:
C₉H₁₈O

[ 分子量 ]:
142.24

[ 闪点 ]:
63.9±0.0 °C

[ 精确质量 ]:
142.135757

[ PSA ]:
17.07000

[ LogP ]:
3.56

[ 外观性状 ]:
棕色液体

[ 蒸汽压 ]:
0.5±0.4 mmHg at 25°C

[ 折射率 ]:
1.418

[ 储存条件 ]:
2-8°C

[ 稳定性 ]:
Stable. Flammable. Incompatible with strong oxidizing agents.

[ 水溶解性 ]:
Practically insoluble

正壬醛MSDS

正壬醛毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RA5700000

CHEMICAL NAME :: 1-Nonanal

CAS REGISTRY NUMBER :: 124-19-6

BEILSTEIN REFERENCE NO. :: 1236701

LAST UPDATED :: 199712

DATA ITEMS CITED :: 14

MOLECULAR FORMULA :: C9-H18-O

MOLECULAR WEIGHT :: 142.27

WISWESSER LINE NOTATION :: VH8

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Kidney, Ureter, Bladder - urine volume increased

TYPE OF TEST :: LC - Lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >9500 mg/m3/4H

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 5 gm/kg/2W-I

TOXIC EFFECTS :: Skin and Appendages - dermatitis, other (after systemic exposure) Skin and Appendages - hair Nutritional and Gross Metabolic - weight loss or decreased weight gain

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 100 umol/L

REFERENCE :: MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 4,277,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83152 No. of Facilities: 94 (estimated) No. of Industries: 2 No. of Occupations: 9 No. of Employees: 21463 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83152 No. of Facilities: 1204 (estimated) No. of Industries: 11 No. of Occupations: 10 No. of Employees: 8081 (estimated) No. of Female Employees: 1350 (estimated)

正壬醛安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S37/39

[ 危险品运输编码 ]:
3082

[ WGK德国 ]:
2

[ RTECS号 ]:
RA5700000

[ 包装等级 ]:
III

[ 危险类别 ]:
9

[ 海关编码 ]:
29121900

正壬醛合成路线

正壬醛上下游产品

正壬醛上游产品

正壬醛下游产品

正壬醛制备

1.工业上由壬醇脱氢来制取。或将壬酸和甲酸的钙盐或钡盐混合，在减压下加热蒸馏而得，也可将甲酸在一氧化锰上由壬酸还原而制得。

2. 烟草：OR，57。

正壬醛海关

[ 海关编码 ]: 2912190090

[ 中文概述 ]:
HS: 2912190090. 其他无环醛（不含其他含氧基）. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 四聚甲醛报明外观

[ Summary ]:
2912190090 acyclic aldehydes without other oxygen function。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

正壬醛文献

Olfactometry Profiles and Quantitation of Volatile Sulfur Compounds of Swiss Tilsit Cheeses.

J. Agric. Food Chem. 63 , 7511-21, (2015)

To establish the odor profiles of three differently fabricated commercial Swiss Tilsit cheeses, analyses were conducted using headspace solid-phase microextraction gas chromatography-mass spectrometry...

Volatile Compounds from Grape Skin, Juice and Wine from Five Interspecific Hybrid Grape Cultivars Grown in Québec (Canada) for Wine Production.

Molecules 20 , 10980-1016, (2015)

Developed from crosses between Vitis vinifera and North American Vitis species, interspecific hybrid grape varieties are becoming economically significant in northern areas, where they are now extensi...

Mosquito odorant receptor for DEET and methyl jasmonate.

Proc. Natl. Acad. Sci. U. S. A. 111(46) , 16592-7, (2014)

Insect repellents are important prophylactic tools for travelers and populations living in endemic areas of malaria, dengue, encephalitis, and other vector-borne diseases. DEET (N,N-diethyl-3-methylbe...

更多文献

正壬醛