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乙酯黄酮

乙酯黄酮用途

Efloxate是一种血管扩张剂,用于治疗慢性冠脉机能不全及心绞痛等。

乙酯黄酮名称

[ CAS 号 ]:
119-41-5

[ 中文名 ]:
乙酯黄酮

[ 英文名 ]:
Efloxate

[中文别名 ]:

[英文别名 ]:

Corosanin
Efloxatum
Recordil
Oxyflavil
Coril
EINECS 204-321-9
Efloxate
Angorlisin
Oxiflavil
Flacethyle

乙酯黄酮生物活性

[ 描述 ]:

Efloxate是一种血管扩张剂,用于治疗慢性冠脉机能不全及心绞痛等。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 心血管疾病

[相关活性小分子]

乙酯黄酮物理化学性质

[ 密度 ]:
1.265g/cm3

[ 沸点 ]:
486.5ºC at 760 mmHg

[ 熔点 ]:
123-124°

[ 分子式 ]:
C₁₉H₁₆O₅

[ 分子量 ]:
324.32700

[ 闪点 ]:
269.1ºC

[ 精确质量 ]:
324.10000

[ PSA ]:
65.74000

[ LogP ]:
3.40190

[ 蒸汽压 ]:
1.28E-09mmHg at 25°C

[ 折射率 ]:
1.59

[ 储存条件 ]:
2-8℃

乙酯黄酮毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AJ1460000

CHEMICAL NAME :: Acetic acid, ((4-oxo-2-phenyl-4H-1-benzopyran-7-yl)oxy)-, ethyl ester

CAS REGISTRY NUMBER :: 119-41-5

BEILSTEIN REFERENCE NO. :: 0313027

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C19-H16-O5

MOLECULAR WEIGHT :: 324.35

WISWESSER LINE NOTATION :: T66 BO EVJ CR& IO1VO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,125,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,125,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 13,561,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,125,1982

乙酯黄酮安全信息

[ 海关编码 ]:
2918990090

乙酯黄酮合成路线

详细合成路线

乙酯黄酮上下游产品

乙酯黄酮上游产品

乙酯黄酮下游产品

乙酯黄酮海关

[ 海关编码 ]: 2918990090

[ 中文概述 ]:
2918990090. 其他含其他附加含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%