微囊藻毒素LR
微囊藻毒素LR用途
微囊藻毒素LR名称
[ CAS 号 ]:
101043-37-2
[ 中文名 ]:
微囊藻毒素(LR亚型)
[ 英文名 ]:
Microcystin-LR
[中文别名 ]:
[英文别名 ]:
- akerstox
- TOXIN,BLUE-GREENALGA
- EINECS 200-659-6
- Microcystin-LR
- microcystin-lr solution
- toxin-lr
- microcystin LR
- MFCD00131607
- 5-L-Arginine-cyanoginosin
- 5-L-Arginine-microcystin LA
微囊藻毒素LR生物活性
[ 描述 ]:
[ 相关类别 ]:
[ 靶点 ]
IC50: 1.7 nM (PP1), 0.04 nM (PP2A)[1].
[体外研究]
[参考文献]
[相关活性小分子]
微囊藻毒素LR物理化学性质
[ 密度 ]:
1.3±0.1 g/cm3
[ 分子式 ]:
C49H74N10O12
[ 分子量 ]:
995.172
[ 闪点 ]:
11 °C
[ 精确质量 ]:
994.548767
[ PSA ]:
340.64000
[ LogP ]:
-1.54
[ 外观性状 ]:
solid film
[ 折射率 ]:
1.598
[ 储存条件 ]:
库房低温,通风,干燥,与食品原料分开存放
[ 水溶解性 ]:
ethanol: 1 mg/mL
微囊藻毒素LRMSDS
微囊藻毒素LR毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GT2810000
- CHEMICAL NAME :
- Cyanoginosin LA, 5-L-arginine-
- CAS REGISTRY NUMBER :
- 101043-37-2
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C49-H74-N10-O12
- MOLECULAR WEIGHT :
- 995.33
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 50 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 26,603,1988
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 50 ug/kg
- TOXIC EFFECTS :
- Cardiac - other changes Liver - hepatitis (hepatocellular necrosis), zonal Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
- REFERENCE :
- TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 8,221,1988
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 18 mg/m3/10M
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 28,605,1990
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 32500 ng/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Kidney, Ureter, Bladder - other changes Skin and Appendages - hair
- REFERENCE :
- JEPOEC Journal of Environmental Pathology, Toxicology and Oncology. (Chem-Orbital, POB 134, Park Forest, IL 60466) V.5(4)- 1984- Volume(issue)/page/year: 9(3),221,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 60 ug/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay) Skin and Appendages - hair
- REFERENCE :
- SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 220,1383,1983
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5200 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 63,215,1987 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2205 ug/kg/6W-I
- TOXIC EFFECTS :
- Liver - other changes Liver - changes in liver weight Related to Chronic Data - death
- REFERENCE :
- AJBSAM Australian Journal of Biological Sciences. (Commonwealth Scientific and Industrial Research Organization, 314 Albert St., E. Melbourne, Vic. 3002, Australia) V.6- 1953- Volume(issue)/page/year: 31,209,1978
微囊藻毒素LR安全信息
[ 符号 ]:
GHS02, GHS06, GHS08
[ 信号词 ]:
Danger
[ 危害声明 ]:
H225-H301-H311-H331-H370
[ 警示性声明 ]:
P210-P260-P280-P301 + P310-P311
[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)
[ 危害码 (欧洲) ]:
T+
[ 风险声明 (欧洲) ]:
26/27/28-36/37/38-43
[ 安全声明 (欧洲) ]:
S26;S45;S36/S37/S39
[ 危险品运输编码 ]:
UN 2811 6.1/PG 1
[ WGK德国 ]:
3
[ RTECS号 ]:
GT2810000
[ 危险类别 ]:
6.1
微囊藻毒素LR合成路线
微囊藻毒素LR文献
Res. Microbiol. 166(2) , 93-101, (2015)
Strain A2 with algicidal activity against Microcystis aeruginosa was isolated and identified with the genus Acinetobacter on the basis of phenotypic tests and 16S rRNA gene analysis. It was identified...
Protein kinase C and P2Y12 take center stage in thrombin-mediated activation of mammalian target of rapamycin complex 1 in human platelets.J. Thromb. Haemost. 12(5) , 748-60, (2014)
Rapamycin, an inhibitor of mammalian target of rapamycin complex-1 (mTORC1), reduces platelet spreading, thrombus stability, and clot retraction. Despite an important role of mTORC1 in platelet functi...
Sensitive detection of microcystin-LR by using a label-free electrochemical immunosensor based on Au nanoparticles/silicon template/methylene blue nanocomposite.J. Nanosci. Nanotechnol. 13(12) , 8245-52, (2013)
A label-free electrochemical immunosensor, based on a gold nanoparticles (Au NPs)/silicon template/methylene blue (MB)/chitosan (CHIT) nanocomposite-modified electrode, was fabricated for the ultrasen...
相关化工产品/化学物质:
推荐生产厂家/供应商:
公司名:上海吉至生化科技有限公司
区域:上海市奉贤区
价格:
¥需询单/1mg
¥需询单/1mg
¥4188.0/1mg
联系人:刘佳
产品详情:微囊藻毒素LR
公司名:上海源溪生物科技有限公司
区域:上海市浦东新区
价格:
¥需询单/1g
联系人:赖经理
产品详情:Microcystin-LR
公司名:上海阿拉丁生化科技股份有限公司
区域:上海市浦东新区
价格:
¥4000.9/1ml
¥需询单/1g
¥需询单/1g
¥需询单/1g
联系人:阿拉丁
产品详情:微囊藻毒素Microcystin-LR
查看所有供应商请点击:
相关化合物
【微囊藻毒素LR】化源网提供微囊藻毒素LRCAS号101043-37-2,微囊藻毒素LRMSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询微囊藻毒素LR上化源网,专业又轻松。>>电脑版:微囊藻毒素LR
标题:微囊藻毒素LR_MSDS_用途_密度_CAS号【101043-37-2】_化源网 地址:https://www.chemsrc.com/amp/cas/101043-37-2_1112890.html