2-(2H3)Furancarboxylic acid

Modify Date: 2024-01-06 23:57:08

2-(2H3)Furancarboxylic acid Structure
2-(2H3)Furancarboxylic acid structure
Common Name 2-(2H3)Furancarboxylic acid
CAS Number 40073-83-4 Molecular Weight 115.102
Density 1.3±0.1 g/cm3 Boiling Point 232.1±13.0 °C at 760 mmHg
Molecular Formula C5HD3O3 Melting Point 129-131°C
MSDS N/A Flash Point 94.2±19.8 °C

 Use of 2-(2H3)Furancarboxylic acid


2-Furoic acid-d3 is the deuterium labeled 2-Furoic acid[1]. 2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation[2]. 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats[3].

 Names

Name 2-furoic-d3 acid
Synonym More Synonyms

 2-(2H3)Furancarboxylic acid Biological Activity

Description 2-Furoic acid-d3 is the deuterium labeled 2-Furoic acid[1]. 2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation[2]. 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats[3].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Wordofa GG, et al. Tolerance and metabolic response of Pseudomonas taiwanensis VLB120 towards biomass hydrolysate-derived inhibitors. Biotechnol Biofuels. 2018 Jul 19;11:199.  

[3]. Hall IH, et al. The hypolipidemic effects of 2-furoic acid in Sprague-Dawley rats. Arch Pharm (Weinheim). 1993 Jan326(1):15-23.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 232.1±13.0 °C at 760 mmHg
Melting Point 129-131°C
Molecular Formula C5HD3O3
Molecular Weight 115.102
Flash Point 94.2±19.8 °C
Exact Mass 115.034874
PSA 50.44000
LogP 0.64
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.513

 Synonyms

Phenol,3,4,5-trichloro-,acetate
(H)Furan-2-carboxylic acid
3,4,5-Trideuteriofuran-2-carbonsaeure
2-(H)Furancarboxylic acid
2-Furan-d-carboxylic acid
3,4,5-Trichlorophenyl acetate