40073-83-4

40073-83-4 structure

Name: 2-(2H3)Furancarboxylic acid
Chemical Name: 2-furoic-d3 acid
CAS Number: 40073-83-4
Molecular Formula: C₅HD₃O₃
Molecular Weight: 115.102
Catalog: Signaling Pathways Metabolic Enzyme/Protease ATP Citrate Lyase
Create Date: 2018-04-20 08:00:00
Modify Date: 2024-01-06 23:57:08
2-Furoic acid-d3 is the deuterium labeled 2-Furoic acid[1]. 2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation[2]. 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats[3].

Name	2-furoic-d3 acid
Synonyms	Phenol,3,4,5-trichloro-,acetate (H)Furan-2-carboxylic acid 3,4,5-Trideuteriofuran-2-carbonsaeure 2-(H)Furancarboxylic acid 2-Furan-d-carboxylic acid 3,4,5-Trichlorophenyl acetate

Description	2-Furoic acid-d3 is the deuterium labeled 2-Furoic acid[1]. 2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation[2]. 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats[3].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> ATP Citrate Lyase Research Areas >> Metabolic Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Wordofa GG, et al. Tolerance and metabolic response of Pseudomonas taiwanensis VLB120 towards biomass hydrolysate-derived inhibitors. Biotechnol Biofuels. 2018 Jul 19;11:199. [3]. Hall IH, et al. The hypolipidemic effects of 2-furoic acid in Sprague-Dawley rats. Arch Pharm (Weinheim). 1993 Jan326(1):15-23.