hCAIX-IN-6

Modify Date: 2024-01-09 22:26:41

hCAIX-IN-6 structure	Common Name	hCAIX-IN-6
	CAS Number	2451479-86-8	Molecular Weight	352.36
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₂N₂O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of hCAIX-IN-6

Compounds 6B and 14g showed significant inhibitory effect on tumor related subtype HCA IX with low nanomolar potency, while 6K was effective on HCA XII. Compounds 6B, 14g and 6K can be considered as the leading molecules for the development of future cancer therapeutic drugs based on new mechanisms of action.

Name	hCAIX-IN-6

Description	Compounds 6B and 14g showed significant inhibitory effect on tumor related subtype HCA IX with low nanomolar potency, while 6K was effective on HCA XII. Compounds 6B, 14g and 6K can be considered as the leading molecules for the development of future cancer therapeutic drugs based on new mechanisms of action.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase
References	[1]. Swain B,et al. New coumarin/sulfocoumarin linked phenylacrylamides as selective transmembrane carbonic anhydrase inhibitors: Synthesis and in-vitro biological evaluation. Bioorg Med Chem. 2020 Aug 1;28(15):115586.

Molecular Formula	C₁₈H₁₂N₂O₄S
Molecular Weight	352.36

hCAIX-IN-6

Use of hCAIX-IN-6

Names

hCAIX-IN-6 Biological Activity

Chemical & Physical Properties