DDO-2213
Modify Date: 2024-04-13 08:32:35
DDO-2213 structure
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Common Name | DDO-2213 | ||
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| CAS Number | 2378768-36-4 | Molecular Weight | 483.97 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H27ClFN7O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DDO-2213DDO-2213 is an orally active and potent WDR5-MLL1 inhibitor, with an IC50 of 29 nM and a Kd value of 72.9 nM for the WDR5 protein. DDO-2213 selectively inhibits MLL (mixed lineage leukemia) histone methyltransferase activity and the proliferation of MLL translocation-harboring cells. DDO-2213 can be used for MLL fusion leukemia research[1]. |
| Name | DDO-2213 |
|---|
| Description | DDO-2213 is an orally active and potent WDR5-MLL1 inhibitor, with an IC50 of 29 nM and a Kd value of 72.9 nM for the WDR5 protein. DDO-2213 selectively inhibits MLL (mixed lineage leukemia) histone methyltransferase activity and the proliferation of MLL translocation-harboring cells. DDO-2213 can be used for MLL fusion leukemia research[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C24H27ClFN7O |
|---|---|
| Molecular Weight | 483.97 |
| InChIKey | LXONEMNSYOAQJT-UHFFFAOYSA-N |
| SMILES | CN1CCN(c2cc(F)c(-c3ccc(C(=O)N(C)C)cc3)cc2Nc2ncnc(Cl)c2N)CC1 |