TCO-PEG8-NHS ester

Modify Date: 2024-01-10 00:43:48

TCO-PEG8-NHS ester structure	Common Name	TCO-PEG8-NHS ester
	CAS Number	2353409-95-5	Molecular Weight	690.78
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₂H₅₄N₂O₁₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TCO-PEG8-NHS ester

TCO-PEG8-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name	TCO-PEG8-NHS ester

Description	TCO-PEG8-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238.

Molecular Formula	C₃₂H₅₄N₂O₁₄
Molecular Weight	690.78