RIPK3-IN-4

Modify Date: 2024-03-30 12:14:19

RIPK3-IN-4 Structure
RIPK3-IN-4 structure
Common Name RIPK3-IN-4
CAS Number 2304617-58-9 Molecular Weight 541.39
Density N/A Boiling Point N/A
Molecular Formula C24H18BrFN4O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RIPK3-IN-4


RIPK3-IN-4 (Compound 42) is a RIPK3 inhibitor. RIPK3-IN-4 inhibits HK-2 cell damage, necroptosis and inflammatory responses. RIPK3-IN-4 reduces Cisplatin (HY-17394)- and I/R-induced kidney damage, inflammatory response and necroptosis in acute kidney injury[1].

 Names

Name RIPK3-IN-4

 RIPK3-IN-4 Biological Activity

Description RIPK3-IN-4 (Compound 42) is a RIPK3 inhibitor. RIPK3-IN-4 inhibits HK-2 cell damage, necroptosis and inflammatory responses. RIPK3-IN-4 reduces Cisplatin (HY-17394)- and I/R-induced kidney damage, inflammatory response and necroptosis in acute kidney injury[1].
Related Catalog
References

[1]. He XY, et al. Compound-42 alleviates acute kidney injury by targeting RIPK3-mediated necroptosis. Br J Pharmacol. 2023 Oct;180(20):2641-2660.  

 Chemical & Physical Properties

Molecular Formula C24H18BrFN4O3S
Molecular Weight 541.39
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