2304617-58-9

2304617-58-9 structure

Name: RIPK3-IN-4
Chemical Name: RIPK3-IN-4
CAS Number: 2304617-58-9
Molecular Formula: C₂₄H₁₈BrFN₄O₃S
Molecular Weight: 541.39
Catalog: Signaling Pathways Apoptosis RIP kinase
Create Date: 2023-12-26 10:35:24
Modify Date: 2025-08-25 14:57:09
RIPK3-IN-4 (Compound 42) is a RIPK3 inhibitor. RIPK3-IN-4 inhibits HK-2 cell damage, necroptosis and inflammatory responses. RIPK3-IN-4 reduces Cisplatin (HY-17394)- and I/R-induced kidney damage, inflammatory response and necroptosis in acute kidney injury[1].

Name	RIPK3-IN-4

Description	RIPK3-IN-4 (Compound 42) is a RIPK3 inhibitor. RIPK3-IN-4 inhibits HK-2 cell damage, necroptosis and inflammatory responses. RIPK3-IN-4 reduces Cisplatin (HY-17394)- and I/R-induced kidney damage, inflammatory response and necroptosis in acute kidney injury[1].
Related Catalog	Signaling Pathways >> Apoptosis >> RIP kinase Research Areas >> Inflammation/Immunology
References	[1]. He XY, et al. Compound-42 alleviates acute kidney injury by targeting RIPK3-mediated necroptosis. Br J Pharmacol. 2023 Oct;180(20):2641-2660.

Molecular Formula	C₂₄H₁₈BrFN₄O₃S
Molecular Weight	541.39