2-Deoxy-D-glucose-13C

Modify Date: 2024-01-11 18:14:14

2-Deoxy-D-glucose-13C Structure
2-Deoxy-D-glucose-13C structure
Common Name 2-Deoxy-D-glucose-13C
CAS Number 201612-55-7 Molecular Weight 165.14900
Density N/A Boiling Point N/A
Molecular Formula C6H12O5 Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of 2-Deoxy-D-glucose-13C


2-Deoxy-D-glucose-13C is the 13C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1][2].

 Names

Name 2-deoxy-d-[1-13c]arabino-hexose

 2-Deoxy-D-glucose-13C Biological Activity

Description 2-Deoxy-D-glucose-13C is the 13C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Zhu Z, et al. 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer Res. 2005 Aug 1;65(15):7023-30.;Ueyama A, et al. Nonradioisotope assay of glucose uptake activity in r

 Chemical & Physical Properties

Molecular Formula C6H12O5
Molecular Weight 165.14900
Exact Mass 165.07200
PSA 90.15000