119897-50-6

119897-50-6 structure

Name: 2-Deoxy-D-glucose-13C-1
Chemical Name: 2-deoxy-d-[6-13c]arabino-hexose
CAS Number: 119897-50-6
Molecular Formula: C₆H₁₂O₅
Molecular Weight: 165.14900
Catalog: Signaling Pathways Anti-infection HSV
Create Date: 2016-05-18 15:18:49
Modify Date: 2024-01-02 18:38:56
2-Deoxy-D-glucose-13C-1 is the 13C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1][2].

Name	2-deoxy-d-[6-13c]arabino-hexose
Synonyms	2-Deoxy-D-glucose-6-13C

Description	2-Deoxy-D-glucose-13C-1 is the 13C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Anti-infection >> HSV Signaling Pathways >> Metabolic Enzyme/Protease >> Hexokinase
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Zhu Z, et al. 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer Res. 2005 Aug 1;65(15):7023-30.;Ueyama A, et al. Nonradioisotope assay of glucose uptake activity in r

119897-49-3

119897-50-6

119897-51-7

Literature: Walker; Ehler; Unkefer Carbohydrate research, 1988 , vol. 181, p. 125 - 134

Precursor 1
119897-49-3
DownStream 0