HIV-1 integrase inhibitor 3

Modify Date: 2024-01-14 10:47:54

HIV-1 integrase inhibitor 3 structure	Common Name	HIV-1 integrase inhibitor 3
	CAS Number	1638504-56-9	Molecular Weight	432.42
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₂F₂N₄O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of HIV-1 integrase inhibitor 3

HIV-1 integrase inhibitor 3 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM.

Name	HIV-1 integrase inhibitor 3

Description	HIV-1 integrase inhibitor 3 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> HIV Integrase Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
Target	IC50: 2.7 nM (INST)[1]
In Vitro	HIV-1 integrase inhibitor 3 (compound 4c) is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM. HIV-1 integrase inhibitor 3 also displays an antiviral inhibitory potency against the Q148H/G140S mutant with an EC50 of 7 nM[1].
References	[1]. Zhao XZ, et al. HIV-1 Integrase Strand Transfer Inhibitors with Reduced Susceptibility to Drug Resistant MutantIntegrases. ACS Chem Biol. 2016 Apr 15;11(4):1074-81.

Molecular Formula	C₂₁H₂₂F₂N₄O₄
Molecular Weight	432.42
Storage condition	2-8℃