HIV-1 integrase inhibitor 9

Modify Date: 2025-08-25 17:17:10

HIV-1 integrase inhibitor 9 Structure
HIV-1 integrase inhibitor 9 structure
Common Name HIV-1 integrase inhibitor 9
CAS Number 2709085-95-8 Molecular Weight 416.30
Density N/A Boiling Point N/A
Molecular Formula C18H12N2O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HIV-1 integrase inhibitor 9


HIV-1 integrase inhibitor 9 (compound 8a) is a potent HIV-1 RNase H inhibitor with an IC50 of 12.3 μM. HIV-1 integrase inhibitor 9 shows an antiviral activity[1].

 Names

Name HIV-1 integrase inhibitor 9

 HIV-1 integrase inhibitor 9 Biological Activity

Description HIV-1 integrase inhibitor 9 (compound 8a) is a potent HIV-1 RNase H inhibitor with an IC50 of 12.3 μM. HIV-1 integrase inhibitor 9 shows an antiviral activity[1].
Related Catalog
Target

HIV-1 RNase H:12.3 nM (IC50)

References

[1]. Dongwei Kang, et al. Discovery, optimization, and target identification of novel coumarin derivatives as HIV-1 reverse transcriptase-associated ribonuclease H inhibitors. Eur J Med Chem. 2021 Dec 5;225:113769.

 Chemical & Physical Properties

Molecular Formula C18H12N2O10
Molecular Weight 416.30
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