Azoxystrobin-d4

Modify Date: 2024-01-02 19:14:59

Azoxystrobin-d4 structure	Common Name	Azoxystrobin-d4
	CAS Number	1346606-39-0	Molecular Weight	407.41
	Density	1.3±0.1 g/cm3	Boiling Point	581.3±50.0 °C at 760 mmHg
	Molecular Formula	C₂₂H₁₃D₄N₃O₅	Melting Point	105-107°C
	MSDS	N/A	Flash Point	305.3±30.1 °C

Use of Azoxystrobin-d4

Azoxystrobin-d4 is deuterium labeled Azoxystrobin. Azoxystrobin is a broad-spectrum β-methoxyacrylate fungicide. Azoxystrobin inhibits mitochondrial respiration by binding to the Qo site of the cytochrome bc1 complex and inhibiting electron transfer. Azoxystrobin induces the production of reactive oxygen species (ROS) and induces cell apoptosis.

Name	Methyl (2E)-2-{2-[(6-{[2-cyano(2H4)phenyl]oxy}-4-pyrimidinyl)oxy]phenyl}-3-methoxyacrylate
Synonym	More Synonyms

Description	Azoxystrobin-d4 is deuterium labeled Azoxystrobin. Azoxystrobin is a broad-spectrum β-methoxyacrylate fungicide. Azoxystrobin inhibits mitochondrial respiration by binding to the Qo site of the cytochrome bc1 complex and inhibiting electron transfer. Azoxystrobin induces the production of reactive oxygen species (ROS) and induces cell apoptosis.
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Enock Mpofu, et al. Azoxystrobin amine: A novel azoxystrobin degradation product from Bacillus licheniformis strain TAB7. Chemosphere. 2021 Jun;273:129663.

Density	1.3±0.1 g/cm3
Boiling Point	581.3±50.0 °C at 760 mmHg
Melting Point	105-107°C
Molecular Formula	C₂₂H₁₃D₄N₃O₅
Molecular Weight	407.41
Flash Point	305.3±30.1 °C
Exact Mass	407.141937
LogP	5.13
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.626
Storage condition	2-8°C

Benzeneacetic acid, 2-[[6-[(6-cyanophenyl-2,3,4,5-d)oxy]-4-pyrimidinyl]oxy]-α-(methoxymethylene)-, methyl ester, (αE)-

Methyl (2E)-2-{2-[(6-{[2-cyano(H)phenyl]oxy}-4-pyrimidinyl)oxy]phenyl}-3-methoxyacrylate

Azoxystrobin-d4

Use of Azoxystrobin-d4

Names

Azoxystrobin-d4 Biological Activity

Chemical & Physical Properties

Synonyms