L-Pyroglutamic acid-d5

Modify Date: 2024-01-02 15:36:45

L-Pyroglutamic acid-d5 Structure
L-Pyroglutamic acid-d5 structure
Common Name L-Pyroglutamic acid-d5
CAS Number 1086136-22-2 Molecular Weight 134.14
Density N/A Boiling Point N/A
Molecular Formula C5H2D5NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of L-Pyroglutamic acid-d5


L-Pyroglutamic acid-d5 is the deuterium labeled L-Pyroglutamic acid. L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism.

 Names

Name d5-(S)-pyroglutamic acid

 L-Pyroglutamic acid-d5 Biological Activity

Description L-Pyroglutamic acid-d5 is the deuterium labeled L-Pyroglutamic acid. L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism.
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Molecular Formula C5H2D5NO3
Molecular Weight 134.14
Exact Mass 134.07400
PSA 66.40000