Ertugliflozin L-pyroglutamic acid
Modify Date: 2025-08-25 05:32:58
Ertugliflozin L-pyroglutamic acid structure
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Common Name | Ertugliflozin L-pyroglutamic acid | ||
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| CAS Number | 1210344-83-4 | Molecular Weight | 565.997 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H32ClNO10 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Ertugliflozin L-pyroglutamic acidErtugliflozin (PF-04971729) L-pyroglutamic acid is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2), with an IC50 of 0.877 nM for h-SGLT2[1]. A drug for the treatment of type 2 diabetes mellitus[2]. |
| Name | Ertugliflozin L-pyroglutamic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Ertugliflozin (PF-04971729) L-pyroglutamic acid is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2), with an IC50 of 0.877 nM for h-SGLT2[1]. A drug for the treatment of type 2 diabetes mellitus[2]. |
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| Related Catalog | |
| Target |
IC50: 0.877 nM (h-SGLT2)[1]. |
| In Vitro | Ertugliflozin (PF-04971729) demonstrates >2000-fold selectivity for SGLT2 inhibition (relative to SGLT1) in vitro[3]. |
| In Vivo | Ertugliflozin (PF-04971729) reveals a concentration-dependent glucosuria after oral administration to rats[3]. |
| References |
| Molecular Formula | C27H32ClNO10 |
|---|---|
| Molecular Weight | 565.997 |
| Exact Mass | 565.171448 |
| Storage condition | 2-8℃ |
| MLU731K321 |