![]() Drotrecogin alfa (activated) structure
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Common Name | Drotrecogin alfa (activated) | ||
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CAS Number | 98530-76-8 | Molecular Weight | N/A | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | N/A | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Drotrecogin alfa (activated)Drotrecogin alfa activated (DrotAA) is recombinant human activated protein C (APC). Drotrecogin alfa activated prevents smoke-induced increases in pulmonary microvascular permeability and proinflammatory cytokine IL-1β in rats. Drotrecogin alfa activated inhibits coagulation and inflammation and promotes fibrinolysis. Drotrecogin alfa activated can be used for severe sepsis reaearch[1][2]. |
Name | Drotrecogin alfa (activated) |
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Description | Drotrecogin alfa activated (DrotAA) is recombinant human activated protein C (APC). Drotrecogin alfa activated prevents smoke-induced increases in pulmonary microvascular permeability and proinflammatory cytokine IL-1β in rats. Drotrecogin alfa activated inhibits coagulation and inflammation and promotes fibrinolysis. Drotrecogin alfa activated can be used for severe sepsis reaearch[1][2]. |
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Related Catalog | |
In Vivo | Drotrecogin alfa activated (0-20 mg/kg, IV immediately following smoke exposure, once) significantly attenuates smoke inhalation injury in a dose-dependent manner at 2 hours after insult. Drotrecogin alfa activated (20 mg/kg) has an improvement of the expiration phase of pulmonary dynamic compliance[2]. |
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