Dodecanedioic acid-d4

Modify Date: 2024-01-10 18:27:04

Dodecanedioic acid-d4 Structure
Dodecanedioic acid-d4 structure
Common Name Dodecanedioic acid-d4
CAS Number 97543-02-7 Molecular Weight 234.32500
Density N/A Boiling Point N/A
Molecular Formula C12H18D4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Dodecanedioic acid-d4


Dodecanedioic acid-d4 is the deuterium labeled Dodecanedioic acid[1]. Dodecanedioic acid (C12) is a dicarboxylic acid with a metabolic pathway intermediate to those of lipids and carbohydrates[2].

 Names

Name 1,12-dodecanedioic-2,2,11,11-d4 acid

 Dodecanedioic acid-d4 Biological Activity

Description Dodecanedioic acid-d4 is the deuterium labeled Dodecanedioic acid[1]. Dodecanedioic acid (C12) is a dicarboxylic acid with a metabolic pathway intermediate to those of lipids and carbohydrates[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Greco AV, et al. The metabolic effect of dodecanedioic acid infusion in non-insulin-dependent diabetic patients. Nutrition. 1998 Apr;14(4):351-7.  

 Chemical & Physical Properties

Molecular Formula C12H18D4O4
Molecular Weight 234.32500
Exact Mass 234.17700
PSA 74.60000
LogP 3.05660