MPEP
Modify Date: 2024-01-05 19:48:47
MPEP structure
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Common Name | MPEP | ||
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| CAS Number | 96206-92-7 | Molecular Weight | 193.24 | |
| Density | N/A | Boiling Point | 336.3ºC at 760mmHg | |
| Molecular Formula | C14H11N | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 144.8ºC | |
Use of MPEPMPEP is a potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. IC50 value: 36 nMTarget: mGluR5Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw. |
| Name | MPEP hydrochloride,2-Methyl-6-(phenylethynyl)pyridinehydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | MPEP is a potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. IC50 value: 36 nMTarget: mGluR5Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw. |
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| Related Catalog | |
| References |
| Boiling Point | 336.3ºC at 760mmHg |
|---|---|
| Molecular Formula | C14H11N |
| Molecular Weight | 193.24 |
| Flash Point | 144.8ºC |
| PSA | 12.89000 |
| LogP | 3.59180 |
| Storage condition | Desiccate at +4°C |
| HS Code | 2933399090 |
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~50%
MPEP CAS#:96206-92-7 |
| Literature: Sorensen, Ulrik S.; Pombo-Villar, Esteban Tetrahedron, 2005 , vol. 61, # 10 p. 2697 - 2703 |
|
~88%
MPEP CAS#:96206-92-7 |
| Literature: Saleh, Samer; Picquet, Michel; Meunier, Philippe; Hierso, Jean-Cyrille Synlett, 2011 , # 19 art. no. D22511ST, p. 2844 - 2848 |
|
~72%
MPEP CAS#:96206-92-7 |
| Literature: Reddy, Police Vishnuvardhan; Srinivas, Pottabathula; Annapurna, Manne; Bhargava, Suresh; Wagler, Jorg; Mirzadeh, Nedaossadat; Kantam, Mannepalli Lakshmi Advanced Synthesis and Catalysis, 2013 , vol. 355, # 4 p. 705 - 710 |
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~%
MPEP CAS#:96206-92-7 |
| Literature: Jaeschke, Georg; Porter, Richard; Buettelmann, Bernd; Ceccarelli, Simona M.; Guba, Wolfgang; Kuhn, Bernd; Kolczewski, Sabine; Huwyler, Joerg; Mutel, Vincent; Peters, Jens-Uwe; Ballard, Theresa; Prinssen, Eric; Vieira, Eric; Wichmann, Juergen; Spooren, Will Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 5 p. 1307 - 1311 |
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~%
MPEP CAS#:96206-92-7 |
| Literature: Nishiwaki, Nagatoshi; Minakata, Satoshi; Komatsu, Mitsuo; Ohshiro, Yoshiki Chemistry Letters, 1989 , p. 773 - 776 |
CAS#:1083-25-6| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| 2-Methyl-6-(phenylethynyl)pyridine hydrochloride |
| MPEP,HCl |
| MFCD02262119 |
| Pyridine, 2-methyl-6-(2-phenylethynyl)-, hydrochloride (1:1) |
| MPEP |
| 2-Methyl-6-(phenylethynyl)pyridine hydrochloride (1:1) |
| 2-methyl-6-phenylethynyl-pyridine |
| 2-Methyl-6-phenylaethinyl-pyridin |