5β-Dutasteride

Modify Date: 2024-01-19 09:55:32

5β-Dutasteride Structure
5β-Dutasteride structure
Common Name 5β-Dutasteride
CAS Number 957229-52-6 Molecular Weight 528.53000
Density 1.303±0.06 g/cm3 (20 °C, 760 mmHg) Boiling Point 620.3±55.0 °C (760 mmHg)
Molecular Formula C27H30F6N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5β-Dutasteride


5β-Dutasteride is the S configuration of Dutasteride. 5β-Dutasteride is a potent inhibitor of both 5 alpha-reductase isozymes[1].

 Names

Name 1H-Indeno[5,4-f]quinoline-7-carboxamide, N-[2,5-bis(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-, (4aR,4bS,6aS,7S,9aS,9bS,11aS)
Synonym More Synonyms

 5β-Dutasteride Biological Activity

Description 5β-Dutasteride is the S configuration of Dutasteride. 5β-Dutasteride is a potent inhibitor of both 5 alpha-reductase isozymes[1].
Related Catalog
References

[1].  Lazier CB, et al. Dutasteride, the dual 5alpha-reductase inhibitor, inhibits androgen action and promotes cell death in the LNCaP prostate cancer cell line. Prostate. 2004 Feb 1;58(2):130-44.

 Chemical & Physical Properties

Density 1.303±0.06 g/cm3 (20 °C, 760 mmHg)
Boiling Point 620.3±55.0 °C (760 mmHg)
Molecular Formula C27H30F6N2O2
Molecular Weight 528.53000
Exact Mass 528.22100
PSA 58.20000
LogP 6.97790

 Synonyms

5β-Dutasteride
5-Beta-Dutasteride
Dutasteride Impurity 2