7-Azido-4-methylcoumarin

Modify Date: 2024-04-02 02:46:53

7-Azido-4-methylcoumarin Structure
7-Azido-4-methylcoumarin structure
Common Name 7-Azido-4-methylcoumarin
CAS Number 95633-27-5 Molecular Weight 201.18100
Density N/A Boiling Point N/A
Molecular Formula C10H7N3O2 Melting Point 117.8°C (lit.)
MSDS USA Flash Point N/A

 Use of 7-Azido-4-methylcoumarin


7-Azido-4-methylcoumarin is a fluorescent hydrogen sulfide (H2S) probe. 7-Azido-4-methylcoumarin serves as a highly sensitive assay for cystathionine β-synthase activity[1].

 Names

Name 7-Azido-4-methyl-2H-chromen-2-one
Synonym More Synonyms

 7-Azido-4-methylcoumarin Biological Activity

Description 7-Azido-4-methylcoumarin is a fluorescent hydrogen sulfide (H2S) probe. 7-Azido-4-methylcoumarin serves as a highly sensitive assay for cystathionine β-synthase activity[1].
Related Catalog
References

[1]. Megan K Thorson, et al. Identification of cystathionine β-synthase inhibitors using a hydrogen sulfide selective probe. Angew Chem Int Ed Engl. 2013 Apr 22;52(17):4641-4.  

 Chemical & Physical Properties

Melting Point 117.8°C (lit.)
Molecular Formula C10H7N3O2
Molecular Weight 201.18100
Exact Mass 201.05400
PSA 79.96000
LogP 2.49596

 Safety Information

RIDADR NONH for all modes of transport

 Articles2

More Articles
Fluorescent probe for highly selective and sensitive detection of hydrogen sulfide in living cells and cardiac tissues.

Analyst 138 , 946-51, (2013)

A coumarin-based fluorescence chemoprobe was developed and evaluated for the selective and sensitive detection of hydrogen sulfide in degassed PBS buffers and fetal bovine serum. Fluorescence detectio...

Identification of cystathionine β-synthase inhibitors using a hydrogen sulfide selective probe.

Angew. Chem. Int. Ed. Engl. 52(17) , 4641-4644, (2013)

Buzzing with activity: A hydrogen sulfide selective fluorogenic probe, 7-azido-4-methylcoumarin (AzMC), serves as a highly sensitive assay for cystathionine β-synthase activity, and is suitable for th...

 Synonyms

MFCD16652405