2-Chloro-N6-(2-hydroxyethyl)adenosine

Modify Date: 2025-09-24 18:03:17

2-Chloro-N6-(2-hydroxyethyl)adenosine Structure
2-Chloro-N6-(2-hydroxyethyl)adenosine structure
Common Name 2-Chloro-N6-(2-hydroxyethyl)adenosine
CAS Number 948298-76-8 Molecular Weight 345.74
Density N/A Boiling Point N/A
Molecular Formula C12H16ClN5O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2-Chloro-N6-(2-hydroxyethyl)adenosine


2-Chloro-N6-(2-hydroxyethyl)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2-Chloro-N6-(2-hydroxyethyl)adenosine

 2-Chloro-N6-(2-hydroxyethyl)adenosine Biological Activity

Description 2-Chloro-N6-(2-hydroxyethyl)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

[2]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C12H16ClN5O5
Molecular Weight 345.74
InChIKey RDZDHAJEWMXENA-IOSLPCCCSA-N
SMILES OCCNc1nc(Cl)nc2c1ncn2C1OC(CO)C(O)C1O
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