Ramucirumab

Modify Date: 2024-01-03 10:24:09

Ramucirumab Structure
Ramucirumab structure
Common Name Ramucirumab
CAS Number 947687-13-0 Molecular Weight 6369.07
Density N/A Boiling Point N/A
Molecular Formula C285H434N74O88S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ramucirumab


Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors[1]. Ramucirumab is a recombinant human immunoglobulin G1 monoclonal antibody that binds to the extracellular binding domain of VEGFR-2 and prevents the binding of VEGFR ligands: VEGF-A, VEGF-C, and VEGF-D[2].

 Names

Name Ramucirumab

 Ramucirumab Biological Activity

Description Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors[1]. Ramucirumab is a recombinant human immunoglobulin G1 monoclonal antibody that binds to the extracellular binding domain of VEGFR-2 and prevents the binding of VEGFR ligands: VEGF-A, VEGF-C, and VEGF-D[2].
Related Catalog
Target

VEGFR-2

References

[1]. Fala L. Cyramza (Ramucirumab) Approved for the Treatment of Advanced Gastric Cancer and Metastatic Non-Small-Cell Lung Cancer. Am Health Drug Benefits. 2015 Mar;8(Spec Feature):49-53.

[2]. Oholendt AL, et al. Ramucirumab: A New Therapy for Advanced Gastric Cancer. J Adv Pract Oncol. 2015 Jan-Feb;6(1):71-5.

 Chemical & Physical Properties

Molecular Formula C285H434N74O88S2
Molecular Weight 6369.07
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