947687-13-0

947687-13-0 structure

Name: Ramucirumab
Chemical Name: Ramucirumab
CAS Number: 947687-13-0
Molecular Formula: C₂₈₅H₄₃₄N₇₄O₈₈S₂
Molecular Weight: 6369.07
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK VEGFR
Create Date: 2018-06-15 19:58:28
Modify Date: 2024-01-03 10:24:09
Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors[1]. Ramucirumab is a recombinant human immunoglobulin G1 monoclonal antibody that binds to the extracellular binding domain of VEGFR-2 and prevents the binding of VEGFR ligands: VEGF-A, VEGF-C, and VEGF-D[2].

Name	Ramucirumab

Description	Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors[1]. Ramucirumab is a recombinant human immunoglobulin G1 monoclonal antibody that binds to the extracellular binding domain of VEGFR-2 and prevents the binding of VEGFR ligands: VEGF-A, VEGF-C, and VEGF-D[2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR
Target	VEGFR-2
References	[1]. Fala L. Cyramza (Ramucirumab) Approved for the Treatment of Advanced Gastric Cancer and Metastatic Non-Small-Cell Lung Cancer. Am Health Drug Benefits. 2015 Mar;8(Spec Feature):49-53. [2]. Oholendt AL, et al. Ramucirumab: A New Therapy for Advanced Gastric Cancer. J Adv Pract Oncol. 2015 Jan-Feb;6(1):71-5.

Molecular Formula	C₂₈₅H₄₃₄N₇₄O₈₈S₂
Molecular Weight	6369.07