TG53

Modify Date: 2023-01-11 21:09:52

TG53 Structure
TG53 structure
Common Name TG53
CAS Number 946369-04-6 Molecular Weight 411.88
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C21H22ClN5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TG53


TG53 is a potent inhibitor of tissue transglutaminase (TG2) and fibronectin (FN) protein-protein interaction. TG53 inhibits formation of a complex with integrin β1 and activation of FAK and c-Src during SKOV3 cell attachment onto FN. TG53 can be used for ovarian cancer research[1].

 Names

Name 5-Chloro-N-(4-{[4-(dimethylamino)-6-methyl-2-pyrimidinyl]amino}phenyl)-2-methoxybenzamide
Synonym More Synonyms

 TG53 Biological Activity

Description TG53 is a potent inhibitor of tissue transglutaminase (TG2) and fibronectin (FN) protein-protein interaction. TG53 inhibits formation of a complex with integrin β1 and activation of FAK and c-Src during SKOV3 cell attachment onto FN. TG53 can be used for ovarian cancer research[1].
Related Catalog
References

[1]. Gary E. Schiltz, et al. Inhibitors of tissue transglutaminase 2 (tg2) and uses thereof. Patent, US20210276960A1. 09/09/2021.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Molecular Formula C21H22ClN5O2
Molecular Weight 411.88
Exact Mass 411.146210
LogP 3.41
Index of Refraction 1.677

 Synonyms

5-Chloro-N-(4-{[4-(dimethylamino)-6-methyl-2-pyrimidinyl]amino}phenyl)-2-methoxybenzamide
Benzamide, 5-chloro-N-[4-[[4-(dimethylamino)-6-methyl-2-pyrimidinyl]amino]phenyl]-2-methoxy-
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  • DC Chemicals Limited
  • China
  • Product Name: TG53
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

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