Inarigivir soproxil
Modify Date: 2024-01-10 08:29:26
Inarigivir soproxil structure
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Common Name | Inarigivir soproxil | ||
|---|---|---|---|---|
| CAS Number | 942123-43-5 | Molecular Weight | 703.615 | |
| Density | 1.8±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C25H34N7O13PS | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Inarigivir soproxilInarigivir soproxil is an agonist of innate immunity and shows potent antiviral activity against resistant hepatitis C virus (HCV) variants, with EC50s of 2.2 and 1.0 μM for HCV 1a/1b in cells of genotype 1 HCV replicon systems. |
| Name | inarigivir soproxil |
|---|---|
| Synonym | More Synonyms |
| Description | Inarigivir soproxil is an agonist of innate immunity and shows potent antiviral activity against resistant hepatitis C virus (HCV) variants, with EC50s of 2.2 and 1.0 μM for HCV 1a/1b in cells of genotype 1 HCV replicon systems. |
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| Related Catalog | |
| Target |
EC50: 2.2/1.0 μM (HCV 1a/1b)[1]. |
| In Vitro | Inarigivir soproxil (SB 9200) is an oral modulator of innate immunity that is believed to act via the activation of the RIG-I and NOD2 pathways. SB 9200 has broad-spectrum antiviral activity against RNA viruses including hepatitis C virus (HCV), norovirus, respiratory syncytial virus and influenza and has demonstrated activity against hepatitis B virus (HBV). Inarigivir soproxil is shown to inhibit HCV replication and the range of inhibition is comparable between genotypes 1a and 1b. Inarigivir soproxil demonstrates pan-genotypic antiviral activity against HCV. Inarigivir soproxil is active against DAA-resistant HCV variants[1]. |
| References |
| Density | 1.8±0.1 g/cm3 |
|---|---|
| Molecular Formula | C25H34N7O13PS |
| Molecular Weight | 703.615 |
| Exact Mass | 703.167297 |
| LogP | -0.66 |
| Index of Refraction | 1.732 |
| Storage condition | 2-8℃ |
| inarigivir soproxil |
| [({[(2R,3S,5R)-5-(6-Amino-9H-purin-9-yl)-3-hydroxytetrahydro-2-furanyl]methoxy}{[(2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl)-2-(hydroxymethyl)-4-methoxytetrahydro-3-furanyl]oxy}phosphoryl)sulfanyl]methyl isopropyl carbonate |
| 365052M0DK |