Difamilast
Modify Date: 2025-08-24 10:17:29
Difamilast structure
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Common Name | Difamilast | ||
|---|---|---|---|---|
| CAS Number | 937782-05-3 | Molecular Weight | 446.444 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | 3H24F2N2O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DifamilastDifamilast (OPA-15406) is a novel potent, selective phosphodiesterase IV (PDE4) inhibitor with preference for PDE4B (IC50=11.2 nM). Dermatitis Phase 2 Clinical |
| Name | Difamilast |
|---|---|
| Synonym | More Synonyms |
| Description | Difamilast (OPA-15406) is a novel potent, selective phosphodiesterase IV (PDE4) inhibitor with preference for PDE4B (IC50=11.2 nM). Dermatitis Phase 2 Clinical |
|---|---|
| References | References 1. Hanifin JM, et al. J Am Acad Dermatol. 2016 Aug;75(2):297-305. View Related Products by Target Phosphodiesterase (PDE) Dermatitis |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Molecular Formula | 3H24F2N2O5 |
| Molecular Weight | 446.444 |
| Exact Mass | 446.165314 |
| LogP | 4.73 |
| Index of Refraction | 1.534 |
| Difamilast |
| N-({2-[4-(Difluoromethoxy)-3-isopropoxyphenyl]-1,3-oxazol-4-yl}methyl)-2-ethoxybenzamide |
| Benzamide, N-[[2-[4-(difluoromethoxy)-3-(1-methylethoxy)phenyl]-4-oxazolyl]methyl]-2-ethoxy- |