PDE5-IN-42
Modify Date: 2025-09-19 17:09:02
PDE5-IN-42 structure
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Common Name | PDE5-IN-42 | ||
|---|---|---|---|---|
| CAS Number | 936449-28-4 | Molecular Weight | 453.53700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H31N7O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PDE5-IN-42PDE5-IN-42 (Compound 42) is a potent and orally active PDE5 inhibitor with an IC50 of 0.04 nM. PDE5-IN-42 maintains selectivity over PDE6 and PDE11[1]. |
| Name | 1-[1-(2-ethoxy-ethyl)-3-ethyl-7-(4-methyl-pyridin-2-ylamino)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-piperidine-4-carboxylic acid |
|---|
| Description | PDE5-IN-42 (Compound 42) is a potent and orally active PDE5 inhibitor with an IC50 of 0.04 nM. PDE5-IN-42 maintains selectivity over PDE6 and PDE11[1]. |
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| Related Catalog | |
| Target |
IC50: 0.04 nM (PDE5)[1] |
| References |
| Molecular Formula | C23H31N7O3 |
|---|---|
| Molecular Weight | 453.53700 |
| Exact Mass | 453.24900 |
| PSA | 118.29000 |
| LogP | 3.31120 |
| InChIKey | IQZQWPRZFLHJFI-UHFFFAOYSA-N |
| SMILES | CCOCCn1nc(CC)c2nc(N3CCC(C(=O)O)CC3)nc(Nc3cc(C)ccn3)c21 |