BRD4 Inhibitor-27

Modify Date: 2024-01-02 18:47:46

BRD4 Inhibitor-27 Structure
BRD4 Inhibitor-27 structure
Common Name BRD4 Inhibitor-27
CAS Number 930039-92-2 Molecular Weight 346.31
Density N/A Boiling Point N/A
Molecular Formula C16H13F3N6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BRD4 Inhibitor-27


BRD4 Inhibitor-27 (compound 6) is a BRD4 inhibitor with IC50 of 9.6 and 11.3 μM for BRD4 BD1 and BRD4 BD2, respectively. BRD4 Inhibitor-27 has the potential to study cancer[1].

 Names

Name BRD4 Inhibitor-27

 BRD4 Inhibitor-27 Biological Activity

Description BRD4 Inhibitor-27 (compound 6) is a BRD4 inhibitor with IC50 of 9.6 and 11.3 μM for BRD4 BD1 and BRD4 BD2, respectively. BRD4 Inhibitor-27 has the potential to study cancer[1].
Related Catalog
Target

BD1:9.6 μM (IC50)

BD2:11.3 μM (IC50)

References

[1]. Kim JH, et al. Crystal structure of [1,2,4] triazolo[4,3- b ]pyridazine derivatives as BRD4 bromodomain inhibitors and structure–activity relationship study . Sci Rep 13, 10805 (2023).

 Chemical & Physical Properties

Molecular Formula C16H13F3N6
Molecular Weight 346.31
InChIKey FZKFDCYCUKXFBX-UHFFFAOYSA-N
SMILES FC(F)(F)c1nnc2ccc(NCCc3c[nH]c4ccccc34)nn12
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