BRD4 Inhibitor-27

Names

[ Name ]:
BRD4 Inhibitor-27

Biological Activity

[Description]:

BRD4 Inhibitor-27 (compound 6) is a BRD4 inhibitor with IC50 of 9.6 and 11.3 μM for BRD4 BD1 and BRD4 BD2, respectively. BRD4 Inhibitor-27 has the potential to study cancer[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain

[Target]

BD1:9.6 μM (IC50)

BD2:11.3 μM (IC50)

[References]

[1]. Kim JH, et al. Crystal structure of [1,2,4] triazolo[4,3- b ]pyridazine derivatives as BRD4 bromodomain inhibitors and structure–activity relationship study . Sci Rep 13, 10805 (2023).

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₁₃F₃N₆

[ Molecular Weight ]:
346.31

Related Compounds

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