DB07268
Modify Date: 2024-01-03 09:20:31
DB07268 structure
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Common Name | DB07268 | ||
|---|---|---|---|---|
| CAS Number | 929007-72-7 | Molecular Weight | 321.333 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 641.6±65.0 °C at 760 mmHg | |
| Molecular Formula | C17H15N5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 341.8±34.3 °C | |
Use of DB07268DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM. |
| Name | 2-({2-[(3-Hydroxyphenyl)amino]-4-pyrimidinyl}amino)benzamide |
|---|---|
| Synonym | More Synonyms |
| Description | DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM. |
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| Related Catalog | |
| Target |
JNK1:9 nM (IC50) CHK1:0.82 μM (IC50) PAK4:5.5 μM (IC50) AKT1:15 μM (IC50) ERK2:25 μM (IC50) |
| In Vitro | DB07268 (Compound 2b) also inhibits CHK1, PAK4, AKT1, and ERK2 with IC50s of 0.82 μM, 5.5 μM, 15 μM, and 25 μM, respectively[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 641.6±65.0 °C at 760 mmHg |
| Molecular Formula | C17H15N5O2 |
| Molecular Weight | 321.333 |
| Flash Point | 341.8±34.3 °C |
| Exact Mass | 321.122589 |
| LogP | 1.96 |
| Appearance of Characters | light yellow solid |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.753 |
| Storage condition | -20°C |
| Benzamide, 2-[[2-[(3-hydroxyphenyl)amino]-4-pyrimidinyl]amino]- |
| 2-({2-[(3-Hydroxyphenyl)amino]-4-pyrimidinyl}amino)benzamide |
| MFCD26960941 |
| DB07268 |