Bisphenol A-4d

Modify Date: 2024-01-06 13:30:08

Bisphenol A-4d Structure
Bisphenol A-4d structure
Common Name Bisphenol A-4d
CAS Number 92739-58-7 Molecular Weight 236.33600
Density N/A Boiling Point 220ºC4 mm Hg(lit.)
Molecular Formula C15H8D8O2 Melting Point 157-159ºC(lit.)
MSDS Chinese USA Flash Point N/A
Symbol GHS05 GHS07 GHS08 GHS09
GHS05, GHS07, GHS08, GHS09
Signal Word Danger

 Use of Bisphenol A-4d


Bisphenol A-d8 is the deuterium labeled Bisphenol A[1]. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[2][3][4].

 Names

Name 2,3,5,6-tetradeuterio-4-[2-(2,3,5,6-tetradeuterio-4-hydroxyphenyl)propan-2-yl]phenol
Synonym More Synonyms

 Bisphenol A-4d Biological Activity

Description Bisphenol A-d8 is the deuterium labeled Bisphenol A[1]. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[2][3][4].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Huang M, et al. Bisphenol A and its analogues bisphenol S, bisphenol F and bisphenol AF induce oxidative stress and biomacromolecular damage in human granulosa KGN cells. Chemosphere. 2020 Apr 9;253:126707.  

[3]. Rubin BS, et al. Bisphenol A: an endocrine disruptor with widespread exposure and multiple effects. J Steroid Biochem Mol Biol. 2011 Oct;127(1-2):27-34.  

 Chemical & Physical Properties

Boiling Point 220ºC4 mm Hg(lit.)
Melting Point 157-159ºC(lit.)
Molecular Formula C15H8D8O2
Molecular Weight 236.33600
Exact Mass 236.16500
PSA 40.46000
LogP 3.42370

 Safety Information

Symbol GHS05 GHS07 GHS08 GHS09
GHS05, GHS07, GHS08, GHS09
Signal Word Danger
Hazard Statements H317-H318-H335-H361f-H411
Precautionary Statements P280-P305 + P351 + P338 + P310
RIDADR NONH for all modes of transport

 Synonyms

2,2-Bis(4-hydroxyphenyl-d4)propane
BisphenolA-(rings-d8)