FPND
Modify Date: 2025-08-25 15:34:00
FPND structure
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Common Name | FPND | ||
|---|---|---|---|---|
| CAS Number | 924866-33-1 | Molecular Weight | 429.493 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 680.3±65.0 °C at 760 mmHg | |
| Molecular Formula | C24H24FN7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 365.2±34.3 °C | |
Use of FPNDA novel specific ROCK1 kinase inhibitor with IC50 of 11.2 uM, without inhibitory activity against ROCK2; prevents atorvastatin-induced cerebral hemorrhage in zebrafish embryos (IC50=17.49 uM), by enhancing endothelial cell-cell junctions through inhibiting the ROCK-mediated VE-cadherin signaling pathway. |
| Name | FPMINT |
|---|---|
| Synonym | More Synonyms |
| Description | A novel specific ROCK1 kinase inhibitor with IC50 of 11.2 uM, without inhibitory activity against ROCK2; prevents atorvastatin-induced cerebral hemorrhage in zebrafish embryos (IC50=17.49 uM), by enhancing endothelial cell-cell junctions through inhibiting the ROCK-mediated VE-cadherin signaling pathway. |
|---|---|
| References | References 1. Li S, et al. Cell Death Discov. 2017 Aug 21;3:17051. View Related Products by Target ROCK |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 680.3±65.0 °C at 760 mmHg |
| Molecular Formula | C24H24FN7 |
| Molecular Weight | 429.493 |
| Flash Point | 365.2±34.3 °C |
| Exact Mass | 429.207733 |
| LogP | 3.57 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.717 |
| 6-{[4-(2-Fluorophenyl)-1-piperazinyl]methyl}-N-(1-naphthyl)-1,3,5-triazine-2,4-diamine |
| 6-[[4-(2-Fluorophenyl)-1-piperazinyl]methyl]-N2-1-naphthalenyl-1,3,5-triazine-2,4-diamine |
| FPMINT |
| 6-{[4-(2-Fluorophenyl)piperazin-1-yl]methyl}-N-(1-naphthyl)-1,3,5-triazine-2,4-diamine |
| 1,3,5-Triazine-2,4-diamine, 6-[[4-(2-fluorophenyl)-1-piperazinyl]methyl]-N2-1-naphthalenyl- |
| 4-((4-(2-Fluorophenyl)piperazin-1-yl)methyl)-6-imino-N-(naphthalen-1-yl)-1,3,5-triazin-2-amine |