ABP 688

Modify Date: 2025-08-25 12:39:08

ABP 688 Structure
ABP 688 structure
 Common Name ABP 688
CAS Number 924298-51-1 Molecular Weight 240.30000
Density N/A Boiling Point N/A
Molecular Formula C15H16N2O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ABP 688


ABP688 is a high affinity human mGluR5 antagonist with anKi of 1.7 nM. Radioisotope-labeled ABP688 can be used as a PET tracer for clinical imaging of the mGlu5 receptor[1].

 Names

Name (Z)-N-methoxy-3-[2-(6-methylpyridin-2-yl)ethynyl]cyclohex-2-en-1-imine
Synonym More Synonyms

 ABP 688 Biological Activity

Description ABP688 is a high affinity human mGluR5 antagonist with anKi of 1.7 nM. Radioisotope-labeled ABP688 can be used as a PET tracer for clinical imaging of the mGlu5 receptor[1].
Related Catalog
Target

human mGluR5:1.7 nM (Ki)

References

[1]. Hintermann S, et al. ABP688, a novel selective and high affinity ligand for the labeling of mGlu5 receptors: identification, in vitro pharmacology, pharmacokinetic and biodistribution studies. Bioorg Med Chem. 2007 Jan 15;15(2):903-14.

 Chemical & Physical Properties

Molecular Formula C15H16N2O
Molecular Weight 240.30000
Exact Mass 240.12600
PSA 34.48000
LogP 2.85420

 Synonyms

abp688
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Chemsrc provides ABP 688(CAS#:924298-51-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of ABP 688 are included as well.>> amp version: ABP 688

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