Levothyroxine acyl glucuronide

Modify Date: 2024-01-12 18:13:01

Levothyroxine acyl glucuronide structure	Common Name	Levothyroxine acyl glucuronide
	CAS Number	909880-81-5	Molecular Weight	952.99400
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₁₉I₄NO₁₀	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Levothyroxine acyl glucuronide

Levothyroxine acyl glucuronide (Thyroxine Acyl-β-D-glucuronide), an endogenous metabolite, is the acyl glucuronide formation of thyroxine (T4)[1].

Name	(2S,3S,4S,5R,6S)-6-[(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoyl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
Synonym	More Synonyms

Description	Levothyroxine acyl glucuronide (Thyroxine Acyl-β-D-glucuronide), an endogenous metabolite, is the acyl glucuronide formation of thyroxine (T4)[1].
Related Catalog	Research Areas >> Metabolic Disease
Target	Endogenous metabolite[1]
In Vitro	Levothyroxine acyl glucuronide is a metabolite of T4 glucuronides after hydrolysis with β-glucuronidase[1].
References	[1]. Tong Z, et al. In vitro glucuronidation of thyroxine and triiodothyronine by liver microsomes and recombinant human UDP-glucuronosyltransferases. Drug Metab Dispos. 2007 Dec;35(12):2203-10.

Levothyroxine Acyl Glucuronide

Thyroxine Glucuronoside

Thyroxine Acyl-|A-D-Glucuronide