Levothyroxine acyl glucuronide

Names

[ CAS No. ]:
909880-81-5

[ Name ]:
Levothyroxine acyl glucuronide

[Synonym ]:
Levothyroxine Acyl Glucuronide
Thyroxine Glucuronoside
Thyroxine Acyl-|A-D-Glucuronide

Biological Activity

[Description]:

Levothyroxine acyl glucuronide (Thyroxine Acyl-β-D-glucuronide), an endogenous metabolite, is the acyl glucuronide formation of thyroxine (T4)[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[Target]

Endogenous metabolite[1]


[In Vitro]

Levothyroxine acyl glucuronide is a metabolite of T4 glucuronides after hydrolysis with β-glucuronidase[1].

[References]

[1]. Tong Z, et al. In vitro glucuronidation of thyroxine and triiodothyronine by liver microsomes and recombinant human UDP-glucuronosyltransferases. Drug Metab Dispos. 2007 Dec;35(12):2203-10.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H19I4NO10

[ Molecular Weight ]:
952.99400

[ Exact Mass ]:
952.71900

[ PSA ]:
189.00000

[ LogP ]:
2.60840

Related Compounds