ICMT-IN-54

Modify Date: 2024-02-06 11:18:06

ICMT-IN-54 structure	Common Name	ICMT-IN-54
	CAS Number	908856-14-4	Molecular Weight	487.74
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₄₅NO₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ICMT-IN-54

ICMT-IN-54 (compound 7c) is an adamantyl analogue and an ICMT inhibitor (IC50=12.4 μM), which can inhibit ICMT Methylation. ICMT-in-54 inhibits BFC (N-biotinyl-(6-aminohexanoic)-S-farnesyl-L-cysteine) methylation in saccharomyces cerevisiae expressing ICMT, which is an indirect effect of inhibiting ICMT methylation[1].

Name	ICMT-IN-54

Description	ICMT-IN-54 (compound 7c) is an adamantyl analogue and an ICMT inhibitor (IC50=12.4 μM), which can inhibit ICMT Methylation. ICMT-in-54 inhibits BFC (N-biotinyl-(6-aminohexanoic)-S-farnesyl-L-cysteine) methylation in saccharomyces cerevisiae expressing ICMT, which is an indirect effect of inhibiting ICMT methylation[1].
Related Catalog	Research Areas >> Cancer
Target	IC50: 12.4 μM (human ICMT)[1]
References	[1]. Donelson JL, et al. Amide-substituted farnesylcysteine analogs as inhibitors of human isoprenylcysteine carboxyl methyltransferase. Bioorg Med Chem Lett. 2006 Aug 15;16(16):4420-3.

Molecular Formula	C₂₉H₄₅NO₃S
Molecular Weight	487.74

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ICMT-IN-54

Use of ICMT-IN-54

Names

ICMT-IN-54 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.