VUF11211

Modify Date: 2024-09-16 11:59:03

VUF11211 Structure
VUF11211 structure
Common Name VUF11211
CAS Number 906556-51-2 Molecular Weight 504.49
Density N/A Boiling Point N/A
Molecular Formula C26H35Cl2N5O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of VUF11211


VUF11211 is an effective antagonist of CXCR3 that acts by extending from the minor pocket into the major pocket of the transmembrane domains.

 Names

Name VUF11211

 VUF11211 Biological Activity

Description VUF11211 is an effective antagonist of CXCR3 that acts by extending from the minor pocket into the major pocket of the transmembrane domains.
References 1. Ganghammer S, Gutjahr J, Hutterer E, Krenn PW, Pucher S, Zelle-Rieser C, Jöhrer K, Wijtmans M, Leurs R, Smit MJ, Gattei V, Greil R, Hartmann TN. Combined CXCR3/CXCR4 measurements are of high prognostic value in chronic lymphocytic leukemia due to negative co-operativity of the receptors. Haematologica. 2016 Mar;101(3):e99-102. doi: 10.3324/haematol.2015.133470. Epub 2015 Nov 20. PubMed PMID: 26589908; PubMed Central PMCID: PMC4815737.

 Chemical & Physical Properties

Molecular Formula C26H35Cl2N5O
Molecular Weight 504.49