906556-51-2
906556-51-2 structure
- Name: VUF11211
- Chemical Name: VUF11211
- CAS Number: 906556-51-2
- Molecular Formula: C26H35Cl2N5O
- Molecular Weight: 504.49
- Catalog: Signaling Pathways GPCR/G Protein CXCR
- Create Date: 2024-09-16 11:59:03
- Modify Date: 2024-09-16 11:59:03
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VUF11211 is an effective antagonist of CXCR3 that acts by extending from the minor pocket into the major pocket of the transmembrane domains.
| Name | VUF11211 |
|---|
| Description | VUF11211 is an effective antagonist of CXCR3 that acts by extending from the minor pocket into the major pocket of the transmembrane domains. |
|---|---|
| References | 1. Ganghammer S, Gutjahr J, Hutterer E, Krenn PW, Pucher S, Zelle-Rieser C, Jöhrer K, Wijtmans M, Leurs R, Smit MJ, Gattei V, Greil R, Hartmann TN. Combined CXCR3/CXCR4 measurements are of high prognostic value in chronic lymphocytic leukemia due to negative co-operativity of the receptors. Haematologica. 2016 Mar;101(3):e99-102. doi: 10.3324/haematol.2015.133470. Epub 2015 Nov 20. PubMed PMID: 26589908; PubMed Central PMCID: PMC4815737. |
| Molecular Formula | C26H35Cl2N5O |
|---|---|
| Molecular Weight | 504.49 |